Absorbable Antibacterial Sutures

Category:

Surgery Line

Product Description

Triclosan-Coated Antibacterial Suture

Principle of bacterial inhibition

The antimicrobial agent triclosan inhibits bacterial colonization on sutures by targeting the Fabl gene of Enoyl-acyl carrier protein reductase (ENR), thereby suppressing fatty acid biosynthesis. This disruption of cell membranes leads to leakage of cellular contents, ultimately resulting in its antibacterial effect.

Bacteriostatic

Methicillin-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus epidermidis

Staphylococcus aureus - Escherichia coli

● In Vitro Study on the Antimicrobial Effects of Triclosan

Both Venill Plus and VICRYL Plus demonstrated significant antibacterial effects, with essentially identical antibacterial zones.

● In vivo antibacterial effects of triclosan

In vivo studies indicate that Venill Plus and VICRYL Plus, when containing comparable concentrations of triclosan, demonstrated similar antibacterial effects in vivo.

● In Vivo Release of Triclosan

Triclosan rapidly dissolved within 6 hours after implantation of Venill Plus (2-0) and VICRYL Plus (2-0) in hamsters, with release rates of 77.59% and 69.86%, respectively.

Release rates exceeded 85% in both the test and control groups after 24 hours. The dissolution profiles of Venill Plus and VICRYL Plus absorbable surgical sutures were essentially identical. These sutures were naturally eliminated through blood and urine, with no adverse effects on the body.

Comparison of Tensile Strength and Retention Rate Between Venill Plus and a Imported Brand of Similar Antibacterial PGLA Sutures

Materials	90% ethylene glycol lactate and 10% L-propylene glycol lactate copolymer (PGLA), Containing the antimicrobial agent triclosan
Suture Diameter Specifications	2, 1, 0, 2-0, 2-0/T, 3-0, and 4-0
Tensile strength	Week 2: 75% Week 3: 50% Week 4: 25% Duration of tension support: 28 days.
Absorption time	56–70 days
Color	Purple
Structure	Multi-strand braiding
Needle Configuration	Standard silver needles, Black needles, and double-hole needles